Variable penetrance may also reflect the action of unlinked modifier genes, epigenetic changes or environmental factors. The penetrance of some pathogenic genotypes is known to be age- and/or sex-dependent. It may also result from differential allelic expression, copy number variation or the modulating influence of additional genetic variants in cis or in trans. Reduced penetrance can be a function of the specific mutation(s) involved or of allele dosage. Reduced penetrance may therefore explain not only why genetic diseases are occasionally transmitted through unaffected parents, but also why healthy individuals can harbour quite large numbers of potentially disadvantageous variants in their genomes without suffering any obvious ill effects. Reduced penetrance is not uncommon indeed, there are many known examples of ‘disease-causing mutations’ that fail to cause disease in at least a proportion of the individuals who carry them. *occasional 'cliff-hangers' or lead-ins to the next book may occur, though generally at least one major plot arc shows completion or at the very least, forward progress.Some individuals with a particular disease-causing mutation or genotype fail to express most if not all features of the disease in question, a phenomenon that is known as ‘reduced (or incomplete) penetrance’. This book in particular has several mentions and flashbacks to past abuse. Please do not read if you are triggered by things like this. *Books MAY contain mentions of abuse, unpleasant situations, etc. *LBGTQ and straight themes (the main character is intersex and will have both male and female lovers, M/F, M/M, F/F, MMMFF etc.) The Not Quite series are novellas (between 35,000-45,000 words) and contains the following:

In general, you probably won't find many alpha males or fainting females, and relationships are more poly. In my books you will find atypical characters and varied sexuality. I love reverse harem, but I got sick of reading the same old tropes. Tension grows, emotions run high, and heads roll.uh, literally.as Sam takes one more step away from their solitary life and toward actually caring about people-or terrifying monsters, whatever. Too bad the raiders, hyena beasts, and giant death worms don't seem to think so.

And helping the idealistic human sovereign move his family member and closest advisor from Golding to Westhold is the right thing to do. Maybe it would just be easier to murder the idiots and leave the bodies in the wastelands.īut, growl as Sam might, everyone knows the hunter will do the right thing. Anything would be more enjoyable than this-even hunting hungry fiends. What's more fun than dragging a politician, an ogre, a leprechaun, and a hired killer across the wastelands to retrieve a human passenger? Anything.

Not Quite Human by Kaye Draper